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Product Description
ST18 Polyclonal Antibody | BS65718 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat,Dog,Horse,Sheep,
Application: WB，FCM，
Application Range: WB=1:500-2000，Flow-Cyt=1ug/test
Background: ST18 is a 1,047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells. ST18 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ST18 Polyclonal Antibody detects endogenous levels of ST18 protein.
Molecular Weight: 110 kD，115 kD
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: KIAA0535; St18; ST18_HUMAN; suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) ; Suppression of tumorigenicity 18 protein; Suppression of tumorigenicity protein 18; Zinc finger protein 387; Znf387.
Immunogen: KLH conjugated synthetic peptide derived from human ST18/Znf387:451-550/1047
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: affinity purified by Protein A
Pathway:
