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Product Description
DOPA Decarboxylase polyclonal Antibody | BS90425 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB IHC
Application Range: WB:1:500-1:1,000 IHC:1:50-1:200
Background: DOPA decarboxylase (DDC), also designated aromatic-L-amino-acid decarboxylase (AADC) belongs to the group II decarboxylase family of proteins. DDC, which can form a homodimer, is an important protein in the catecholamine biosynthesis pathway. DDC acts as a catalyst in the decarboxylation of L-5-hydroxytryptophan to serotonin, L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-tryptophan to tryptamine. Defects in the gene encoding for DDC may cause the autosomal recessive disorder AADC deficiency. AADC deficiency is an early onset inborn error in neurotransmitter metabolism which can lead to catecholamine and serotonin deficiency. This causes poor feeding, psychomotor and developmental delays, lethargy, ptosis, gastrointestinal disturbances and hypothermia.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: DOPA Decarboxylase polyclonal Antibody detects endogenous levels of DOPA Decarboxylase protein.
Molecular Weight: 53 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: AADC, DDC, AADC, Aromatic L Amino Acid Decarboxylase, Aromatic-L-amino-acid decarboxylase, Ddc, DDC, DOPA decarboxylase (aromatic L-amino acid decarboxylase), DOPA decarboxylase,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
