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Product Description
DTX2 polyclonal Antibody | BS8881 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200
Background: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: DTX2 polyclonal Antibody detects endogenous levels of DTX2 protein.
Molecular Weight: ~ 67kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Probable E3 ubiquitin-protein ligase DTX2; Protein deltex-2; Deltex2; hDTX2; RING finger protein 58; DTX2; KIAA1528; RNF58
Immunogen: Recombinant full length Human DTX2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
