Product Description
HNP-1 monoclonal Antibody | MB9273 | Bioworld
Host: Mouse
Reactivity: Human, Rat
Application: WB IHC
Application Range: WB:1:500-1:2,000 IHC:1:50-1:200
Background: Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: HNP-1 monoclonal Antibody detects endogenous levels of HNP-1 protein.
Molecular Weight: 10 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: HP-1, HP1, HP-2, HP2, DEFA1, DEF1, DEFA2, MRS, alpha 1, DEF1, DEF1, DEFA1, DEFA1B, DEFA2, Defensin 1, Defensin, Defensin, alpha 1, Defensin, alpha 1, myeloid related sequence, Defensin, alpha 2, HNP-1, HNP-2, HNP1, HP-1, HP-2, HP1, HP2, MRS, Myeloid related sequence, Neutrophil defensin 1, Neutrophil defensin 2,
Immunogen: Peptide
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProG affinity purified
Pathway: