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Product Description
IgG4 Rabbit monoclonal Antibody | BS9949M | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB IHC
Application Range: WB: 1:1000-1:5000 IHC: 1:50-1:200
Background: The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of IgG4 and does not cross-react with related proteins.
Molecular Weight: ~ 36 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Ig gamma-4 chain C region; IGHG4
Immunogen: Recombinant Antibody.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein A affinity purified
Pathway:
