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Product Description
LAMP2a polyclonal Antibody | BS90788 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse
Application: WB IHC
Application Range: WB:1:500 IHC:1:50-1:200
Background: Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107A) and LAMP-2 (also designated CD107B) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans Golgi network and are transported intracellularly via a pathway that is distinct from the clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: LAMP2a polyclonal Antibody detects endogenous levels of LAMP2a protein.
Molecular Weight: N/A
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: LAMP-2, Lysosome-associated membrane protein 2, LAMP2, CD107 antigen-like family member B, CD107b, LAMP 2, Lamp 2a, LAMP-2, LAMP2, LAMP2, Lysosome-associated membrane glycoprotein 2, Lysosome-associated membrane protein 2,
Immunogen: Synthetic peptide within C-terminal human LAMP2a.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Peptide affinity purified.
Pathway:
