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Product Description
NUDT15 polyclonal Antibody | BS71189 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB IHC
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200
Background: NUDT15 (nudix (nucleoside diphosphate linked moiety X) -type motif 15), also known as MTH2, is a 164 amino acid protein that belongs to the nudix hydrolase family and uses magnesium as a cofactor to catalyze the conversion of 8-oxo-dGTP to 8-oxo-dGMP and diphosphate. Via its catalytic activity, NUDT15 mediates the hydrolysis of select nucleoside diphosphate derivatives and may play a role in the prevention of DNA transversions. The gene encoding NUDT15 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NUDT15 polyclonal Antibody detects endogenous levels of NUDT15 protein.
Molecular Weight: ~ 19 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: MTH2; Probable 8-oxo-dGTP diphosphatase NUDT15
Immunogen: Recombinant protein of human NUDT15.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
