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Product Description
OGG1 polyclonal Antibody | BS90982 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB IHC
Application Range: WB:1:500 IHC:1:50-1:200
Background: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: OGG1 polyclonal Antibody detects endogenous levels of OGG1 protein.
Molecular Weight: 39 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: AP lyase, OGG1, MMH, MUTM, OGH1, 8 hydroxyguanine DNA glycosylase, 8 oxoguanine DNA glycosylase 1, 8 oxoguanine DNA glycosylase, AP lyase, DNA (apurinic or apyrimidinic site) lyase, DNA apurinic or apyrimidinic site lyase, DNA lyase, DNA- (apurinic or apyrimidinic site) lyase, HMMH, HOGG 1, HOGG1, MMH, MUTM, N glycosylase, Ogg 1, Ogg1, OGG1, OGH 1, OGH1,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
