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Product Description
Prealbumin polyclonal Antibody | BS91105 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB IHC IP
Application Range: WB:1:1,000-1:2,000 IHC:1:50-1:200
Background: Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein) . The gene encoding Prealbumin maps to human chromosome 18q12.1.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Prealbumin polyclonal Antibody detects endogenous levels of Prealbumin protein.
Molecular Weight: 16 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: TTR, Amyloid polyneuropathy, Amyloidosis I, ATTR, Carpal tunnel syndrome 1, CTS, CTS1, Dysprealbuminemic euthyroidal hyperthyroxinemia, Dystransthyretinemic hyperthyroxinemia, Epididymis luminal protein 111, HEL111, HsT2651, PALB, Prealbumin amyloidosis type I, Prealbumin, Prealbumin Thyroxine-binding, Senile systemic amyloidosis, TBPA, Thyroxine binding prealbumin, Transthyretin, TTHY, TTR, TTR protein,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
