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Product Description
PRMT5 polyclonal Antibody | BS6835 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat,Monkey
Application: WB IHC IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200
Background: PRMT5, also designated JAK-binding protein 1), (JBP1), pICln, and two novel factors. PRMT5 binds the Sm proteins via their Arginine- and Glycine-rich (RG) domains, while pICln binds the Sm domains. PRMT5 is a distinct member of the protein-Arginine methyltransferase (PRMT) family, and predominantly localizes to the cytoplasm in a wide variety of tissues. PRMT5 also associates specifically with the transcription start site region of the cyclin E1 promoter, and, therefore, is involved in the control of transcription and proliferation.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PRMT5 polyclonal Antibody detects endogenous levels of PRMT5 protein.
Molecular Weight: ~ 70 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Protein arginine N-methyltransferase 5; 72 kDa ICln-binding protein; Histone-arginine N-methyltransferase PRMT5; Jak-binding protein 1; Shk1 kinase-binding protein 1 homolog; SKB1 homolog; SKB1Hs; PRMT5; HRMT1L5; IBP72; JBP1; SKB1
Immunogen: Recombinant full length Human PRMT5.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
