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Product Description
PROK2 polyclonal Antibody | BS8369 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Background: Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PROK2 polyclonal Antibody detects endogenous levels of PROK2 protein.
Molecular Weight: ~ 14 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Prokineticin-2; PK2; Protein Bv8 homolog; PROK2; BV8
Immunogen: Recombinant full length Human PROK2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
