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Product Description
TFPT polyclonal Antibody | BS8235 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IF
Application Range: WB: 1:500~1:2000 IHC/IF: 1:50~1:200
Background: TFPT (TCF3 fusion partner), also known as INO80F or protein FB1, is a 253 amino acid nuclear protein. TFPT is a component of the chromatin-remoldeling INO80 complex, which is composed of proteins such as BAF53, ACTR5, ACTR8, INOC1, INO80B, INO80C, INO80D and INO80E. The INO80 complex, in addition to chromatin-remoldeling, plays a role in DNA repair, DNA replication, checkpoint regulation, telomere maintenance and chromosome segregation. TFPT interacts with ARC and appears to promote apoptosis in a TP53/p53-independent manner. It is also thought that a chromosomal aberration involving the genes that encode TFPT and E2A is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL) .
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TFPT polyclonal Antibody detects endogenous levels of TFPT protein.
Molecular Weight: ~ 28 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: TCF3 fusion partner; INO80 complex subunit F; Protein FB1; TFPT; INO80F
Immunogen: Recombinant full length Human TFPT.
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A
