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Product Description
Anti-DYNC1LI1 monoclonal Antibody | MB62227 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: FC, IF, WB
Application Range: WB 1:2000, IF 1:100, FLOW 1:100
Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: dynein cytoplasmic 1 light intermediate chain 1
Molecular Weight: 56.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DLC-A; DNCLI1; LIC1
Immunogen: Full length human recombinant protein of human DYNC1LI1 (NP_057225) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
