Product Description
Anti-PSMD10 monoclonal Antibody | MB62384 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: FC, WB
Application Range: WB 1:2000, Flow 1:100
Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: proteasome 26S subunit, non-ATPase 10
Molecular Weight: 24.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: dJ889N15.2; p28; p28 (GANK)
Immunogen: Full length human recombinant protein of human PSMD10 (NP_002805) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A