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Product Description
ATIC monoclonal Antibody | MB62547 | Bioworld
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Dog
Application: FC, WB
Application Range: WB 1:500~2000, FLOW 1:100
Background: This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Molecular Weight: 64.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH
Immunogen: Full length human recombinant protein of human ATIC (NP_004035) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
