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Product Description
BEST3 (Bestrophin 3) monoclonal Antibody | MB62602 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: FC, IF, WB
Application Range: WB 1:2000, IF 1:100, FLOW 1:100
Background: BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336) . Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]) . [supplied by OMIM]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: bestrophin 3
Molecular Weight: 50.8 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: VMD2L3
Immunogen: Full length human recombinant protein of human BEST3 (NP_689652) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
