Product Description
CD86 Rabbit monoclonal Antibody | BS9900M | Bioworld
Host: Rabbit
Reactivity: Human, Rat, Cynomolgus Monkey
Application: WB ICC/IF IHC FC
Application Range: WB: 1:1000-1:2000 IHC/ICC/IF: 1:50-1:200 FC: 1:50-1:100
Background: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of CD86 and does not cross-react with related proteins.
Molecular Weight: ~ 37, 70 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Activation B7-2 antigen 3; Activation B7-2 antigen; Activation B72 antigen; B lymphocyte activation antigen B7 2; B lymphocyte activation antigen B72; B-lymphocyte activation antigen B7-2 2; B-lymphocyte activation antigen B7-2; B7 2; B7 2 antigen; B7; B7-2; B7.2; B70; B72 antigen; BU63; CD 86; CD28 antigen ligand 2 2; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD28LG2; CD86; CD86 antigen; 2; CD86 antigen; CD86 molecule; CD86; CLS1; CTLA 4 counter recep
Immunogen: Recombinant Antibody.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein A affinity purified
Pathway: