Product Description
FOXO3A polyclonal Antibody | BS90530 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse
Application: WB ICC IHC FC
Application Range: WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: FOXO3A polyclonal Antibody detects endogenous levels of FOXO3A protein.
Molecular Weight: 71 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FOXO3, FKHRL1, FOXO3A, AF6q21, AF6q21 protein, DKFZp781A0677, FKHR2, FKHRL 1, FKHRL1, FKHRL1P2, Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1, Forkhead box O3, Forkhead box O3A, Forkhead box protein O3, Forkhead box protein O3A, Forkhead Drosophila homolog of in rhabdomyosarcoma like 1, Forkhead homolog (rhabdomyosarcoma) like 1, Forkhead in rhabdomyosarcoma like 1, Forkhead in rhabdomyosarcoma-like 1, FOX O3A, FOXO2, foxo3, FOXO3, FOXO3A, MGC12739, MGC31925,
Immunogen: Peptide
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Peptide affinity purified
Pathway: