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Product Description
GST3 monoclonal Antibody | MB9257 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: WB IHC FC
Application Range: WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:100
Background: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hypermethylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hypermethylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.
Storage & Stability: Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Specificity: GST3 monoclonal Antibody detects endogenous levels of GST3 protein.
Molecular Weight: 23 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GST class-pi, GSTP1-1, Deafness, Deafness X-linked 7, DFN7, FAEES3, Fatty Acid Ethyl Ester Synthase III, Glutathione S Transferase 3, Glutathione S Transferase Pi, Glutathione S-transferase P, Glutathione S-transferase pi 1, GST class-pi, GST3, GSTP, Gstp1, GSTP1-1, GSTP1, PI, X linked 7 Antibody
Immunogen: Recombinant protein within Human GST3 aa 1-150.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein affinity purified.
Pathway:
