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Product Description
Histone H2B (acetyl K20) polyclonal Antibody | BS94093 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC IP FC
Application Range: WB:1:1,000 ICC:1:100-1:500 IHC:1:100-1:500 FC:1:50-1:100
Background: Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Histone H2B (acetyl K20) polyclonal Antibody detects endogenous levels of Histone H2B protein only when acetylated at K20.
Molecular Weight: 14 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Hist1h2ba, H2B 1A, H2B, H2B histone family, H2B2f, H2B2F, H2Ba, H2Bf, HIST2H2BF, histone H2B, histone H2B type 1, Histone H2B type 2-F, MGC131639,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Acetylated
Purification & Purity: ProA affinity purified
Pathway:
