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Product Description
Histone H3 (mono-methyl K36) Rabbit monoclonal Antibody | BS9873M | Bioworld
Host: Rabbit
Reactivity: Human, Mouse
Application: WB ICC/IF
Application Range: WB: 1:1000-1:2000 ICC: 1:50-1:200
Background: Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination. These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of histone H3 only when mono-methylated at Lys36.
Molecular Weight: ~ 17 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: H3K36me1
Immunogen: Recombinant Antibody.
Conjugate: Unconjugated
Modification: Methylated
Purification & Purity: Protein A affinity purified
Pathway:
