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Product Description
HSPB8 (Hsp22) monoclonal Antibody | MB63603 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: FC, IF, WB
Application Range: WB 1:500~2000, IF 1:100, FLOW 1:100
Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: heat shock protein family B (small) member 8
Molecular Weight: 21.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22
Immunogen: Full length human recombinant protein of human HSPB8 (NP_055180) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
