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Product Description
Integrin β3 polyclonal Antibody | BS90726 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB IHC FC
Application Range: WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100
Background: Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Integrin β3 polyclonal Antibody detects endogenous levels of Integrin β3 protein.
Molecular Weight: 87/110 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GPIIIa, ITGB3, GP3A, Antigen identified by monoclonal Antibody L230, CD 51, CD 61, CD51, CD51 antigen, CD61, CD61 antigen, DKFZp686A08142, GP3A, GPIIIa, Integrin alpha V, Integrin alpha V vitronectin receptor alpha polypeptide, Integrin alpha V vitronectin receptor alpha polypeptide antigen CD51, integrin alpha-V, Integrin alpha-V light chain, Integrin beta 3, Integrin beta 3 platelet glycoprotein IIIa antigen CD61, Integrin beta chain beta 3, integrinVbeta3, ITAV, ITGAV, ITGB 3, ITGB3, MSK 8, MSK8, Platelet glycoprotein IIIa, Platelet glycoprotein IIIa precursor, Platelet membrane glycoprotein IIIa, Vitronectin receptor alpha polypeptide, vitronectin receptor, Vitronectin receptor subunit alpha, VNR 1, VNR1, VNRA,
Immunogen: Peptide
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Peptide affinity purified
Pathway:
