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Product Description
JMJD6 (N-terminus) monoclonal Antibody | MB0100 | Bioworld
Host: Mouse
Reactivity: Human
Application: WB ICC
Application Range: WB: 1:1000 ICC: 1:100~200
Background: Cells undergoing apoptosis lose the asymmetry of plasma membrane phospholipids, and phosphatidylserine is exposed on the outer surface of the membrane. The phosphatidylserine receptor (PSR) specifically recognizes phosphatidylserine and this binding triggers the phagocytosis of apoptotic cells by either macrophages or dendritic cells. PSR is expressed on the surface of macrophages, fibroblasts, and epithelial cells, and it has been detected in high levels in heart, skeletal muscle, and kidney tissues and is extensively glycosylated. The mammalian phosphatidylserine receptor displays significant homology to Caenorhabditis elegans and Drosophila melanogaster proteins, which suggests that PSR has been conserved throughout phylogeny.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of JMJD6 and does not cross-react with related proteins
Molecular Weight: Predicted band size:46KDa Observed band size:62KDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PSR; PTDSR; PTDSR1; KIAA0585; jumonji domain containing 6; Lysyl-hydroxylase JMJD6; Phosphatidylserine receptor; PTDSR; KIAA0585; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; PSR; Peptide-lysine 5-dioxygenase JMJD6; Protein PTDSR
Immunogen: Synthetic peptide, corresponding to the N-terminus of Human JMJD6.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Dopamine Signaling in Parkinson's Disease Plathway,
