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Product Description
L1CAM monoclonal Antibody | MB63779 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: FC, IF, WB
Application Range: WB 1:2000, IF 1:100, FLOW 1:100
Background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus) . Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: L1 cell adhesion molecule
Molecular Weight: 137.8 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1
Immunogen: Full length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
