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Product Description
MBD3 polyclonal Antibody | BS90828 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC IF IHC FC IP
Application Range: WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: Methylation of DNA contributes to the regulation of gene transcription in both mammalian and invertebrate systems. DNA methylation predominates on cytosine residues that are present in dinucleotide motifs consisting of a 5′ cytosine followed by guanosine (CpG), and it requires the enzymatic activity of DNA methyltransferase, which results in transcriptional repression of the methylated gene. Several proteins have been identified that associate with the methyl-CpG sites, and they include methyl-CpG binding protein-1 (MBD1), MBD2, MBD3, MBD4 and MeCP2. Expression of the MBD proteins is highest in somatic tissues.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: MBD3 polyclonal Antibody detects endogenous levels of MBD3 protein.
Molecular Weight: 33 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: MBD3, AI181826, AU019209, MBD 3, Mbd3, MBD3: methyl CpG binding domain protein 3, MBD3, Methyl CpG binding domain protein 3, Methyl CpG binding protein MBD3, Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
