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Product Description
mGluR2 polyclonal Antibody | BS90852 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC
Application Range: WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200
Background: The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors) . The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-2, which may interact with GRASP, acts as a receptor for glutamate. It may also be involved in the regulation of neurotransmission suppression and in synaptogenesis or synaptic stablization.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: mGluR2 polyclonal Antibody detects endogenous levels of mGluR2 protein.
Molecular Weight: 96 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: mGluR2, GRM2, AMPA selective glutamate receptor 2, GLUR2, GLURB, Glutamate metabotropic receptor 2, Glutamate receptor homolog, Glutamate receptor metabotropic 2, GPRC1B, GRM2, GRM2, Metabotropic glutamate receptor 2, mGlu2, mGluR2, OTTHUMP00000210984, OTTHUMP00000210986,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
