Product Description
MSI2 polyclonal Antibody | BS90885 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC FC
Application Range: WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to post-translational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: MSI2 polyclonal Antibody detects endogenous levels of MSI2 protein.
Molecular Weight: 35/37 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Musashi-2, MSI2, FLJ36569, MGC3245, Msi2, MSI2/HOXA9 fusion gene, included, MSI2H, MSI2H, Musashi 2, Musashi homolog 2, Musashi RNA binding protein 2, Musashi, Drosophila, homolog of, 2, Musashi-2, RNA binding protein Musashi homolog 2, RNA-binding protein Musashi homolog 2, WD 40 repeat protein MSI2,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: