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Product Description
p38 MAPK polyclonal Antibody | BS91002 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC
Application Range: WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200
Background: MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: p38 MAPK polyclonal Antibody detects endogenous levels of p38 MAPK protein.
Molecular Weight: 41 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: MAP kinase 14, MAPK 14, CSAID-binding protein, CSBP, MAP kinase p38 alpha, SAPK2a, MAPK14, CSAID-binding protein, Csaids binding protein, CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX-interacting protein 2, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, MK14, Mxi2, p38, p38 MAP kinase, p38 mitogen activated protein kinase, p38ALPHA, p38alpha Exip, PRKM14, PRKM15, RK, SAPK2A, Stress-activated protein kinase 2a,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
