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Product Description
UHRF1 (N-terminus) monoclonal Antibody | MB0055 | Bioworld
Host: Mouse
Reactivity: Human,Mouse
Application: WB ICC
Application Range: WB: 1:1000 ICC: 1:50~200
Background: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of UHRF1 (N-terminus) and does not cross-react with related proteins
Molecular Weight: Predicted band size:90KDa Observed band size:90KDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Np95; hNP95; ICBP90; RNF106; FLJ21925; MGC138707; E3 ubiquitin-protein ligase UHRF1; Nuclear protein 95; HuNp95; hNp95; RING finger protein 106;
Immunogen: Synthetic peptide, corresponding to the N-terminus of Human UHRF1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
