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Product Description
Calreticulin monoclonal Antibody | MB9109 | Bioworld
Host: Mouse
Reactivity: Human
Application: WB IHC ICC FC
Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: Calnexin and calregulin (also called calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum, Calnexin to the membrane and calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor calregulin contains the calcium-binding "E-F hand" motif found in calmodulins. Calnexin and calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: Calreticulin monoclonal Antibody detects endogenous levels of Calreticulin protein.
Molecular Weight: 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ERp60, CALR, CRTC, Autoantigen RO, CALR, CALR protein, CALR, Calregulin, Calreticulin, cC1qR, CRP55, CRT, CRTC, Endoplasmic reticulum resident protein 60, Epididymis secretory sperm binding protein Li 99n, ERp60, FLJ26680, grp60, HACBP, HEL S 99n, RO, Sicca syndrome antigen A (autoantigen Ro; calreticulin), Sicca syndrome antigen A, SSA,
Immunogen: Recombinant protein.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProG affinity purified.
Pathway:
