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Product Description
JunB polyclonal Antibody | BS90755 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IP
Application Range: WB:1:1,000-1:2,000 ICC:1:50-1:200
Background: The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein along with c-Fos is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE) . Two additional genes, Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: JunB polyclonal Antibody detects endogenous levels of JunB protein.
Molecular Weight: 43 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: JUNB, Activator protein 1, AP 1, AP1, Jun B, Jun B proto oncogene, Jun B protooncogene, Junb, JunB proto oncogene, JunB protoncogene 9, JunB protooncogene, JUNB, Transcription factor jun B, Transcription factor jun-B, Transcription factor junB,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
