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Product Description
TFF1 polyclonal Antibody | BS91331 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB ICC/IF IHC IP FC
Application Range: WB:1:500 ICC/IF:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 IP:1:10-1:50
Background: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: TFF1 polyclonal Antibody detects endogenous levels of TFF1 protein.
Molecular Weight: N/A
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: hP1.A, BCEI, PS2, TFF1, BCEI, Breast cancer estrogen inducible protein, Breast cancer estrogen inducible sequence, Breast cancer estrogen-inducible protein, D21S21, Gastrointestinal trefoil protein, Gastrointestinal trefoil protein pS2, hP1.A, HP1A, HPS 2, HPS2, pNR 2, PNR-2, pNR2, Polypeptide P1.A, Protein pS2, PS 2, pS2, pS2 protein, TFF 1, TFF1, TFF1, Trefoil factor 1,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
