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Product Description
a-Myb (D259) polyclonal Antibody | BS1924 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t (14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: A-Myb (D259) polyclonal Antibody detects endogenous levels of A-Myb protein.
Molecular Weight: ~ 85 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Myb-related protein A; A-Myb; Myb-like protein 1; MYBL1; AMYB
Immunogen: Synthetic peptide, corresponding to amino acids 221-270 of Human a-Myb.
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A
