Product Description
ADH5 polyclonal Antibody | BS6512 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB 1:500 - 1:2000
Background: ADH5 (alcohol dehydrogenase 5 (class III) ), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ADH5 polyclonal Antibody detects endogenous levels of ADH5 protein.
Molecular Weight: ~ 40 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Alcohol dehydrogenase class-3; Alcohol dehydrogenase 5; Alcohol dehydrogenase class chi chain; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S- (hydroxymethyl) glutathione dehydrogenase; ADH5; ADHX; FDH
Immunogen: Recombinant full length Human ADH5.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: