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Product Description
BMPR2 polyclonal Antibody | BS60120 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB: 1:500~1:1000
Background: Members of the transforming growth factor β superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP) -2, BMP-4, and osteogenic protein (OP) -1 (also designated BMP-7) . BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: BMPR2 polyclonal Antibody detects endogenous levels of BMPR2 protein.
Molecular Weight: ~ 115 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Bone morphogenetic protein receptor type-2; BMP type-2 receptor; BMPR-2; Bone morphogenetic protein receptor type II; BMP type II receptor; BMPR-II; BMPR2; PPH1
Immunogen: A synthetic peptide corresponding to residues in Human BMPR2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
![[KO Validated] BMPR2 Polyclonal Antibody](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/295374/455511/sab-signalway-antibody__92073.1641690747__22193.1641691382.gif?c=2 "[KO Validated] BMPR2 Polyclonal Antibody")
