Product Description
DPPA4 polyclonal Antibody | BS72135 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB 1:500 - 1:2000
Background: This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: DPPA4 polyclonal Antibody detects endogenous levels of DPPA4 protein.
Molecular Weight: 38kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: 2410091M23Rik
Immunogen: Recombinant protein of human DPPA4
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: