Euro
USD
British Pound
NULL
Product Description
GRM1 polyclonal Antibody | BS60765 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB
Application Range: WB: 1:500~1:1000
Background: The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors) . The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-1, which can form a homodimer acts as a receptor for glutamate. It may also be involved in glutamate activity in the CNS.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GRM1 polyclonal Antibody detects endogenous levels of GRM1 protein.
Molecular Weight: ~ 132 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Metabotropic glutamate receptor 1; mGluR1; GRM1; GPRC1A; MGLUR1
Immunogen: A synthetic peptide corresponding to residues in Human GRM1
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
