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Product Description
MAGEA9 polyclonal Antibody | BS61025 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types as well as in normal testis and placenta. MAGE-A9 (melanoma-associated antigen 9), also known as MAGE9 or CT1.9 (cancer/testis antigen 1.9), is a 315 amino acid protein that contains one MAGE domain. Like most MAGE family members, MAGE-A9 is expressed in several types of tumors, including lung cancer, breast cancer and melanoma, and is thought to play an important role in tumor progression and transformation. Additionally, MAGE-A9 may be involved in embryonic development.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MAGEA9 polyclonal Antibody detects endogenous levels of MAGEA9 protein.
Molecular Weight: ~ 35 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Melanoma-associated antigen 9; Cancer/testis antigen 1.9; CT1.9; MAGE-9 antigen; MAGEA9; MAGE9; MAGEA9A; MAGEA9B
Immunogen: A synthetic peptide corresponding to residues in Human MAGEA9.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Immune checkpoint signaling in the Tumor Microenvironment,T cell receptor signaling,
