Product Description
NAA15 polyclonal Antibody | BS2134 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: NARG1 (NMDA (N-methyl-δ-aspartate) receptor-regulated gene 1), also known as NATH (N-terminal acetyltransferase), TBDN100 (tubedown-1) or Ga19 (gastric cancer antigen Ga19), is a cytoplasmic protein that contains eight TPR repeats. NARG1 is expressed at high levels in dividing tissues such as bone marrow, testis and embryonal brain and it is overexpressed in papillary thyroid carcinomas. NARG1 interacts with ARD1 or ARD2 forming a complex that exhibits N-terminal (α) acetyltransferase activity. The complex interacts with ribosomal subunits functioning in cotranslational acetylation. During apoptosis, both NARG1 and ARD1 are cleaved by caspases which results in decreased acetyltransferase activity. Knockdown of NARG1 in HeLa cells leads to apoptosis, indicating that properly functioning NARG1 is essential for cell viability. In addition, this suggests NARG1 as a potential target in cancer therapy
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NARG1 polyclonal Antibody detects endogenous levels of NARG1 protein.
Molecular Weight: ~ 101 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: N-alpha-acetyltransferase 15, NatA auxiliary subunit; Gastric cancer antigen Ga19; N-terminal acetyltransferase; NMDA receptor-regulated protein 1; Protein tubedown-1; Tbdn100; NAA15; GA19; NARG1; NATH; TBDN100
Immunogen: Synthetic peptide, corresponding Human NARG1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: