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Product Description
PKM2 polyclonal Antibody | BS6443 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IF IP RIP
Application Range: WB: 1:500~1:2000 IHC/IF: 1:50~1:200 IP/RIP: 1:50~1:200
Background: The PKM2 (pyruvate kinase, muscle) gene encodes the M1- and M2-type isoenzymes through alternative splicing events. Both M1- and M2-type isoforms exists as tetramers and are stimulated by fructose 1,6-bisphosphate. In addition, both isoforms exhibit thyroid hormone binding activity and may be referred to as CTHBP (cytosolic thyroid hormone-binding protein) or THBP1.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PKM2 polyclonal Antibody detects endogenous levels of PKM2 protein.
Molecular Weight: ~ 58 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CTHBP; Cytosolic thyroid hormone binding protein; Cytosolic thyroid hormone-binding protein; KPYM; MGC3932; OIP 3; OIP-3; Oip3; OIP3; OPA interacting protein 3; Opa-interacting protein 3; p58; PK Muscle type; PK; muscle type; PK2; Pk3; PKM; PKM2; PYKM; Pyruvate kinase 2/3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; TCB; THBP1; Thyroid hormone binding protein 1; Thyroid hormone binding protein cytosolic; Thyroid hormone
Immunogen: Recombinant full length Human PKM2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: SAPK JNK Signaling Cascades,Signaling Pathways Activating p38 MAP Kinase
