Product Description
POLR3D (N314) polyclonal Antibody | BS3854 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Eukaryotes produce 3 distinct classes of RNA polymerase, Pol I, II and III. Each polymerase is responsible for the synthesis of a different class of RNA. RNA polymerase III (Pol III) transcribes the 5S rRNA genes and all of the tRNA (transfer RNA) genes. POLR3D, also known as DNA-directed RNA polymerase III subunit RPC4 and Protein BN51, is a 398 amino acid nuclear protein that is one of the seventeen subunits that comprise Pol III. Specifically, POLR3D is a DNA-dependent RNA polymerase that uses the four ribonucleoside triphosphates to catalyze the transcription of DNA to RNA. The gene encoding POLR3D maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: POLR3D (N314) pAb detects endogenous levels of POLR3D protein.
Molecular Weight: ~ 38 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DNA-directed RNA polymerase III subunit RPC4; RNA polymerase III subunit C4; DNA-directed RNA polymerase III subunit D; Protein BN51; RNA polymerase III 47 kDa subunit; RPC53 homolog; BN51; BN51T; POLR3D
Immunogen: Synthetic peptide, corresponding to amino acids 281-330 of Human POLR3D.
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A