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Product Description
PRDM10 polyclonal Antibody | BS60764 | Bioworld
Host: Rabbit
Reactivity: Human,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: The PR-domain containing proteins (PRDMs) have a common involvement in the modulation of gene activities. A PR-domain family member usually produces two products, which differ by the presence or absence of the PR domain. The PR-plus product is underexpressed or disrupted, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be a determining cause of malignancy. PRDM10 (PR domain containing 10), also known as PFM7 or TRIS, is a 1,147 amino acid protein that contains ten C2H2-type zinc fingers and one SET domain. Existing as six alternatively spliced isoforms, PRDM10 localizes nucleus and may be involved in transcriptional regulation. PRDM10 may also play a role in the development of the central nerve system, as well as in the pathogenesis of neuronal storage disease.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PRDM10 polyclonal Antibody detects endogenous levels of PRDM10 protein.
Molecular Weight: ~ 130 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PR domain zinc finger protein 10; PR domain-containing protein 10; Tristanin; PRDM10; KIAA1231; PFM7; TRIS
Immunogen: A synthetic peptide corresponding to residues in Human PRDM10
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
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