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Product Description
RBM22 polyclonal Antibody | BS70916 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB 1:500 - 1:2000
Background: RBM22, also designated Zinc finger CCCH domain-containing protein 16, is a highly conserved RNA binding protein that is predominantly expressed in spleen and is localized to the nucleus. With a RRM (RNA recognition motif domain) and a C3H1-type zinc finger, RBM22 is primarily involved in pre-mRNA splicing. In the presence of RBM22, cytosolic ALG-2 (Apoptosis Linked Gene 2) translocates to the nucleus, suggesting a functional interaction between the two proteins. Homologs of RBM22 are essential proteins in the regulation of alternative splicing in the cell cycle, zebrafish development and Drosophilia heart development.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: RBM22 polyclonal Antibody detects endogenous levels of RBM22 protein.
Molecular Weight: ~ 47 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Pre-mRNA-splicing factor RBM22; RNA-binding motif protein 22; Zinc finger CCCH domain-containing protein 16; RBM22; ZC3H16
Immunogen: Recombinant protein of human RBM22.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
