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Product Description
TNFSF14 polyclonal Antibody | BS61000 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB: 1:500~1:1000
Background: Herpes virus entry mediator (HVEM), a type I transmembrane protein, is a member of the TNF receptor superfamily. HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD) . HVEM also binds two cellular ligands, secreted lymphotoxin α and light. LIGHT is a member of the TNF superfamily produced by activated T cells. This type II transmembrane protein competes with HSV glycoprotein D for binding to HVEM. LIGHT is closely related in sequence to lymphotoxin β (LTβ) and can also bind to the LTβ receptor. LIGHT is also known to induce apoptosis and suppress tumor formation.The gene encoding LIGHT maps to human chromosome 19p13.3.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TNFSF14 polyclonal Antibody detects endogenous levels of TNFSF14 protein.
Molecular Weight: ~ 26 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Tumor necrosis factor ligand superfamily member 14; Herpes virus entry mediator ligand; HVEM-L; Herpesvirus entry mediator ligand; CD258; Cleaved into the following 2 chains; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; TNFSF14; HVEML; LIGHT; UNQ391; PRO726
Immunogen: A synthetic peptide corresponding to residues in Human TNFSF14.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
