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Product Description
UACA polyclonal Antibody | BS71782 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB 1:500 - 1:2000
Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: UACA polyclonal Antibody detects endogenous levels of UACA protein.
Molecular Weight: 163kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: NUCLING
Immunogen: Recombinant protein of human UACA
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
![UACA Antibody [UACA/1222]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575296/811831/porsci_lo__79508.1648973713__63771.1649091885.png?c=2 "UACA Antibody [UACA/1222]")
