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Product Description
UBE4A polyclonal Antibody | BS5971 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: UBE4A (ubiquitin conjugation factor E4 A), also known as E4, UFD2 or UBOX2, is a 1,066 amino acid protein that functions in the multiubiquitin pathway of protein degradation. Expressed in cortical neurons and in tubular kidney cells, UBE4A is the human homolog of the Sacch-aromyces cerevisiae UFD2 protein and functions with the UBE (ubiquitin enzymes) proteins to catalyze ubiquitin chain assembly. UBE4A may be in-volved in cell growth and differentiation and can act as an autoantigen in scleroderma, a disease characterized by excessive deposits of collagen in the skin or other organs. Two isoforms of UBE4A exist due to alternative splicing events.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: UBE4A polyclonal Antibody detects endogenous levels of UBE4A protein.
Molecular Weight: ~ 125 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Ubiquitin conjugation factor E4 A; KIAA0126
Immunogen: Synthetic peptide, corresponding to amino acids 183-228 of Human UBE4A.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
