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Product Description
ZNF541 polyclonal Antibody | BS61550 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB
Application Range: WB: 1:500~1:1000
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF541 (zinc finger protein 541) is a 1,365 amino acid nuclear protein that acts as a component of a chromatin remodeling multiprotein complex involved in spermatogenesis. Existing as three alternatively spliced isoforms, ZNF541 interacts with both HSPA2 and HDAC1, and contains one SANT domain, a ELM2 domain and five C2H2-type zinc fingers. The gene encoding ZNF541 maps to human chromosome 19q13.33. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is the genetic home for a number of immunoglobulin (Ig) superfamily members, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs) .
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ZNF541 polyclonal Antibody detects endogenous levels of ZNF541 protein.
Molecular Weight: ~ 160 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Zinc finger protein 541
Immunogen: Synthetic peptide, corresponding to amino acids 361-405 of Human ZNF541
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Pathway:
