Product Description
DOCK2 polyclonal Antibody | BS72336 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB,IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: DOCK2 polyclonal Antibody detects endogenous levels of DOCK2 protein.
Molecular Weight: ~ 240 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: IMD40
Immunogen: A synthetic peptide of human DOCK2
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: