Euro
USD
British Pound
NULL
Product Description
FoxO4 (K447) polyclonal Antibody | BS1842 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IF
Application Range: WB: 1:500~1:1000 IF: 1:50~1:200
Background: FOX4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FoxO4 (K447) polyclonal Antibody detects endogenous levels of FoxO4 protein.
Molecular Weight: ~ 65 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Forkhead box protein O4; Fork head domain transcription factor AFX1; AFX; AFX1; MLLT7; FOXO4
Immunogen: Synthetic peptide, corresponding to amino acids 418-465 of Human FoxO4.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Phosphoinosotode Signaling,PI3K AKT signaling,Hypoxia Signaling,Warburg Effect,Insulin &Glucose Signaling,Glutamine Metabolism,MTOR signaling,ErbB HER Signaling,
